Get Control and Prediction of Solid-State of Pharmaceuticals: PDF

By Rajni Miglani Bhardwaj

ISBN-10: 3319275542

ISBN-13: 9783319275543

ISBN-10: 3319801694

ISBN-13: 9783319801698

This thesis investigates a number of experimental and computational techniques for the invention of stable varieties. additionally, we achieve, as readers, a greater knowing of the most important components underpinning solid-structure and variety. an incredible a part of this thesis highlights experimental paintings performed on structurally very related compounds. one other very important part contains the effect of small alterations in constitution and substituents on solid-structure and variety utilizing computational instruments together with crystal constitution prediction, PIXEL calculations, Xpac, Mercury and statistical modeling instruments. moreover, the writer provides a quick proven procedure for solid-state shape screening utilizing Raman microscopy on multi-well plates to discover the experimental crystallization area. This thesis illustrates a cheap, functional and exact technique to expect the crystallizability of natural compounds in keeping with molecular constitution by myself, and also highlights the molecular elements that inhibit or advertise crystallization.


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Control and Prediction of Solid-State of Pharmaceuticals: Experimental and Computational Approaches (Springer Theses) by Rajni Miglani Bhardwaj

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